| Vaccine | Manufacturer | Doses | Effectiveness vs Infection (%) | Effectiveness vs Hospitalization (%) | Effectiveness vs Death (%) |
|---|---|---|---|---|---|
| BNT162b2 | Pfizer | 2 | 75 | 90 | 95 |
| mRNA-1273 | Moderna | 2 | 80 | 92 | 97 |
| NVX-CoV2373 | Novavax | 2 | 78 | 91 | 96 |
| Ad26.COV2.S | Johnson & Johnson | 1 | 65 | 85 | 90 |
| ChAdOx1 | AstraZeneca | 2 | 70 | 88 | 93 |
| BNT162b2 (Booster) | Pfizer | 3 | 85 | 95 | 98 |
| mRNA-1273 (Booster) | Moderna | 3 | 88 | 96 | 99 |
| CoronaVac | Sinovac | 2 | 60 | 82 | 88 |
| BBIBP-CorV | Sinopharm | 2 | 58 | 80 | 87 |
| Sputnik V | Gamaleya | 2 | 72 | 89 | 94 |
| Covaxin | Bharat Biotech | 2 | 66 | 84 | 91 |
| ZF2001 | Anhui Zhifei | 3 | 62 | 83 | 89 |
| CanSino | CanSinoBIO | 1 | 64 | 86 | 92 |
| Abdala | CIGB | 3 | 67 | 87 | 93 |
| Soberana 02 | Finlay Institute | 3 | 69 | 88 | 94 |
mRNA Vaccines
Pfizer and Moderna vaccines consistently show the highest effectiveness, particularly against hospitalization and death. Booster doses further increase protection, exceeding 95% effectiveness in severe outcomes.
Non-mRNA Vaccines
Viral vector and inactivated vaccines provide strong protection against severe disease, though their effectiveness against infection is lower. These vaccines remain critical in global vaccination efforts.
Glossary of Terms
- Vaccine Effectiveness
- The reduction in disease occurrence among vaccinated individuals.
- Hospitalization Rate
- The percentage of infected individuals requiring hospital care.
- mRNA Vaccine
- A vaccine that uses messenger RNA to stimulate an immune response.
- Viral Vector Vaccine
- A vaccine that delivers genetic material using a harmless virus.
- Real-World Data
- Health data collected outside of controlled clinical trials.